Christina Barkauskas
Durham, United States
Wesley Christina Barkauskas is a pulmonologist, intensivist, and stem cell biologist (Assistant Professoressor of Medicine - Pulmonary, Allergy, and Critical Care Medicine at Duke University). She has extensive experience with multi-site COVID therapeutic trials, and has extensive basic science background with expertise in understanding the fundamental mechanisms involved in lung injury and repair and in exploring novel treatments for acute respiratory distress syndrome (ARDS). As a practicing pulmonary and critical care physician, she is an expert in management of patients with lung disorders, critical illness, and the sequelae thereof. She is currently the co-chair of ACTIV3b/TESICO: Therapeutics for Severely Ill Inpatients with COVID-19, a multi-site international platform study evaluating the safety and efficacy of aviptadil vs. placebo in patients with ARDS.Self, MD, MPH is the Vice President for Clinical Research Networks & Strategy at Vanderbilt University Medical Center, a practicing emergency physician, and clinical researcher. He leads a team of investigators and study personnel that has successfully conducted numerous clinical trials and epidemiologic programs during the past decade in ARDS, sepsis, and pneumonia. He has published over 180 peer reviewed manuscripts, was named one of the top 90 pneumonia researchers in the world in 2018 and co-authored the 2021 American College of Emergency Physicians sepsis guidelines. He is the principal investigator of several multicenter research programs, including the CDC-funded IVY Network, which is a national program investigating the epidemiology of respiratory viruses and vaccines effectiveness, and the clinical coordinating center for the NHLBI-funded ACTIV-4 host response clinical trials platform, which is a program investigating host-targeted investigational drugs for the treatment of COVID-19.
